Nursing Interventions for Hepatitis C Elderly Patients to Reduce the Side Effects of Pegylated Interferon and Ribavirin and Improve their Quality of Life

Alam, Raefa; Fadila, Doaa El-Sayed; Shiha, Gamal El-Sayed

doi:10.21608/asalexu.2014.208807

Nursing Interventions for Hepatitis C Elderly Patients to Reduce the Side Effects of Pegylated Interferon and Ribavirin and Improve their Quality of Life

Document Type : Research articles

Authors

¹ Gerontological Nursing, Faculty of Nursing, Mansoura University

² Internal Medicine; GIT and liver unit, Faculty of Medicine, Mansoura University

10.21608/asalexu.2014.208807

Abstract

Side effects from hepatitis C treatment can be uncomfortable, sometimes debilitating
and rarely even life-threatening for elderly people. With the right planning and support,
many of these side effects can be managed which will help in complying with the treatment
and in turn improve the quality of life. Objective: To identify the effect of nursing intervention
for hepatitis C elderly patients to reduce the side effects of pegylated interferon and ribavirin
and improve their quality of life. Setting: The study was carried out at the outpatient clinics
of the Specialized Medical Hospital, the General Mansoura Hospital, and the Egyptian Liver
Hospital in Dakahlia. Subjects: The study comprised 66 elderly patients with HCV divided
into two equal groups of 33 each. Tools: Data was collected using six tools: an interview
schedule sheet to assess the socio-demographic and health profile of elders, the short form-36
health survey questionnaire, a checklist to identify medication side effects, fatigue severity
scale, geriatric depression scale and nursing intervention program. Results: The main side
effects from treatment as reported by the elderly were fatigue, insomnia, bone ache, heart
burn, fever, itching and stomatitis respectively. Elderly patients in the study group showed
significant improvement in their ratings of perceived fatigue at both 8 and 12 weeks post
intervention, while fatigue level for those in the control group did not show any significant
change in both evaluations. As well significance improvement in the quality of life post 12
week of intervention in study group was observed. Conclusion: It can be concluded that the
side effects and quality of life mean scores improved significantly in the study group
compared to control group after 8 and 12 weeks of nursing intervention. Recommendations:
Caregivers of elders undergoing hepatitis C treatment should support, motivate and
encourage elders to cope with side effects of the hepatitis C therapy.

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